Definition
Death of body tissue due to lack of blood supply or bacterial infection, resulting in decay. When parts of you decide to check out permanently—not coming back from this one.
Example Usage
The diabetic patient's untreated foot wound progressed to gangrene, necessitating below-knee amputation.
Origin
From Greek 'gangraina' meaning 'eating sore'
Fun Fact
Gas gangrene produces a distinctive crackling sensation under the skin called crepitus, caused by bacteria producing actual gas in the tissue.
Source: Vascular surgery and infectious disease terminology
Related Terms
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